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Posted on 13. Mai 2018 · Posted in Allgemein

In healthy subjects, prasugrel increased bupropion cmax and auc values by 14 and 18 , respectively, and decreased cmax and auc values of hydroxybupropion, an active metabolite of bupropion, by 32 and 24 , respectively.

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the effect of hepatic impairment on the pharmacokinetics of bupropion was characterized in 2 single-dose trials, one in subjects with alcoholic liver disease and one in subjects with mild-to-severe cirrhosis.

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bupropion is an effective medication in smoking cessation and has a good safety and side-effect profile aubin et al.

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here bupropion was compared to buspirone augmenting option after failing citalopram monotherapy.

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animals were allowed to self-administer nomifensine, bupropion 8 weeks or water 6 weeks on a chronic basis.


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